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Eva Novotna


Eva Novotna

Charles University, Czech Republic

Biography

Eva Novotna has her expertise in the preparation and purification of recombinant enzymes. She studies interactions of potential inhibitors with carbonyl reducing enzymes using human recombinant enzymes and cancer cell lines. Her research interest include: carbonyl reducing enzymes, inhibitors and cancer drug resistance.

Abstract

Abstract : Roscovitine and purvalanol A effectively inhibit aldo-keto reductase 1C3 (AKR1C3) in vitro and synergistically potentiate cytotoxic effect of daunorubicin