25^th European Toxicology and Applied Pharmacology

Excitotoxicity

Excitotoxicity is the pathological process by which neurons are damaged. They killed by the over activations of receptors. The excitatory neuro transmitter glutamate, such as the NMDA receptor and AMPA receptor.
Glutamate excitotoxicity is a broad and rapidly evolving field of study with many important nuances that have necessarily been oversimplified or, unfortunately, omitted from this review for the sake of reasonable brevity.